Kezhong Zhang Selected Research

Acute-Phase Reaction

1/2017	CREBH Maintains Circadian Glucose Homeostasis by Regulating Hepatic Glycogenolysis and Gluconeogenesis.
11/2016	CREBH Couples Circadian Clock With Hepatic Lipid Metabolism.
10/2008	Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H.
2/2006	Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response.

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Kezhong Zhang Research Topics

Disease

29	Parkinson Disease (Parkinson's Disease) 05/2024 - 12/2008
14	Inflammation (Inflammations) 11/2023 - 07/2008
11	Neoplasms (Cancer) 03/2024 - 02/2011
8	Insulin Resistance 01/2022 - 01/2012
7	Non-alcoholic Fatty Liver Disease 02/2024 - 03/2014
6	Dyskinesias (Dyskinesia) 03/2024 - 10/2019
6	Breast Neoplasms (Breast Cancer) 09/2020 - 01/2012
4	Metabolic Diseases (Metabolic Disease) 03/2024 - 06/2010
4	Fibrosis (Cirrhosis) 02/2024 - 12/2015
4	Obesity 01/2023 - 01/2018
4	Acute-Phase Reaction 01/2017 - 02/2006
3	Tremor (Tremors) 03/2024 - 01/2016
3	Wounds and Injuries (Trauma) 03/2023 - 10/2016
3	Hypertriglyceridemia 01/2023 - 03/2014
3	Hyperglycemia 09/2022 - 01/2012
3	Type 2 Diabetes Mellitus (MODY) 01/2022 - 05/2015
3	Cardiovascular Diseases (Cardiovascular Disease) 12/2015 - 08/2003
2	Pain (Aches) 03/2024 - 08/2015
2	Demyelinating Diseases (Demyelinating Disease) 01/2024 - 02/2023
2	Tauopathies 11/2023 - 05/2023
2	Alzheimer Disease (Alzheimer's Disease) 11/2023 - 05/2023
2	Anemia 10/2023 - 08/2009
2	Body Weight (Weight, Body) 05/2023 - 01/2021
2	Atrophy 02/2023 - 01/2023
2	Fatty Liver 01/2023 - 10/2016
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2023 - 12/2015
2	Stroke (Strokes) 01/2022 - 01/2018
2	Glucose Intolerance 01/2021 - 01/2013
2	Multiple System Atrophy 01/2021 - 09/2010
2	Vascular System Injuries 12/2020 - 01/2017
2	Diabetes Mellitus 01/2013 - 01/2012
2	Hepatocellular Carcinoma (Hepatoma) 09/2012 - 01/2012
1	Dementia (Dementias) 05/2024
1	Cognitive Dysfunction 05/2024
1	Kidney Neoplasms (Kidney Cancer) 03/2024
1	Vascular Remodeling 02/2024
1	Cystic Fibrosis (Mucoviscidosis) 02/2024
1	Liver Cirrhosis (Hepatic Cirrhosis) 02/2024
1	Inborn Genetic Diseases (Disease, Hereditary) 02/2024
1	Liver Diseases (Liver Disease) 02/2024
1	Lung Diseases (Lung Disease) 02/2024
1	Alcoholic Fatty Liver 02/2024
1	Weight Gain 02/2024
1	Constipation 01/2024
1	Iron Overload 10/2023
1	Iron Deficiencies 10/2023
1	Neuroinflammatory Diseases 02/2023
1	Prodromal Symptoms 02/2023

Drug/Important Bio-Agent (IBA)

15	LipidsIBA 01/2023 - 06/2010
14	Proteins (Proteins, Gene)FDA Link 11/2023 - 10/2008
9	Carrier Proteins (Binding Protein)IBA 11/2023 - 10/2008
8	Levodopa (L Dopa)FDA LinkGeneric 03/2024 - 01/2016
7	EnzymesIBA 01/2023 - 01/2012
6	Particulate MatterIBA 01/2022 - 10/2010
6	Insulin (Novolin)FDA Link 01/2022 - 01/2012
6	Transcription Factors (Transcription Factor)IBA 01/2019 - 02/2006
4	SynucleinsIBA 01/2024 - 01/2021
4	IronIBA 10/2023 - 08/2009
4	fibroblast growth factor 21IBA 02/2023 - 03/2014
4	Inositol (Myoinositol)IBA 12/2021 - 01/2018
4	ElementsIBA 01/2017 - 10/2008
3	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2024 - 01/2023
3	Glucose (Dextrose)FDA LinkGeneric 05/2023 - 01/2021
3	CytokinesIBA 02/2023 - 09/2013
2	Biomarkers (Surrogate Marker)IBA 05/2024 - 11/2015
2	Monounsaturated Fatty AcidsIBA 03/2024 - 12/2021
2	Apomorphine FDA Link 11/2023 - 05/2023
2	Prescription DrugsIBA 11/2023 - 05/2023
2	Heme Oxygenase-1IBA 11/2023 - 05/2023
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 03/2023 - 01/2020
2	Toll-Like Receptor 2IBA 02/2023 - 10/2020
2	HomocysteineIBA 02/2023 - 08/2003
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2023 - 01/2018
2	Phosphotransferases (Kinase)IBA 01/2023 - 01/2017
2	Blood Glucose (Blood Sugar)IBA 01/2022 - 01/2018
2	MicroRNAs (MicroRNA)IBA 09/2020 - 03/2016
2	Phenobarbital (Luminal)FDA Link 09/2020 - 06/2012
2	EndoribonucleasesIBA 09/2020 - 01/2018
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2019 - 06/2014
2	LipopolysaccharidesIBA 01/2017 - 10/2016
2	Lysine (L-Lysine)FDA Link 12/2015 - 01/2012
2	Factor VIII (Coagulation Factor VIII)IBA 04/2011 - 11/2008
1	Fatty Acid DesaturasesIBA 03/2024
1	N 30IBA 03/2024
1	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 03/2024
1	CEACAM1 ProteinIBA 02/2024
1	alpha2 Subunit Collagen Type IIBA 02/2024
1	Collagen Type I (Type I Collagen)IBA 02/2024
1	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 02/2024
1	(2S,3R,4R,5S,6R)- 2- (4- chloro- 3- (4- ethoxybenzyl)phenyl)- 6- (methylthio)tetrahydro- 2H- pyran- 3,4,5- triolIBA 02/2024
1	tezacaftor drug combination ivacaftor elexacaftorIBA 02/2024
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 03/2023
1	Transforming Growth Factor beta (TGF-beta)IBA 03/2023
1	Becaplermin (PDGF-BB)FDA Link 03/2023
1	X-Box Binding Protein 1IBA 03/2023
1	Carnitine (L-Carnitine)FDA LinkGeneric 01/2023
1	Matrix Metalloproteinases (MMPs)IBA 01/2023
1	NADP (NADPH)IBA 01/2023

Therapy/Procedure

8	Therapeutics 03/2024 - 07/2008
1	Transcranial Magnetic Stimulation 11/2023